NIJMEGEN (The Thursday Times) — The Lancet Psychiatry mein shaya clinical tajurbat ke ek bare tajziye ke mutabiq antidepressant dawa escitalopram depression kam karne aur use wapas aane se rokne, donon mein sab se acha kaam karti hai.
Netherlands ke Radboud University Medical Center ke muhaqqiqeen ki qiyadat mein ek bainul aqwami team ne 115 be-tarteeb clinical tajurbat ke shawahid yakja kiye, jin mein 30 hazar se zaid afraad shamil thay. Unhon ne 20 antidepressants ka ek doosre se aur sab se maroof antidepressant fluoxetine, yani Prozac, se muwazna kiya.
Teen dawaen dirpa behtari lane mein fluoxetine se behtar rahin: escitalopram, agomelatine, aur duloxetine. Escitalopram lene wale mareezon mein dawa chhorne ka imkan bhi kam tha. Muhaqqiqeen ka kehna hai ke yeh antidepressants ka mukhtasar aur taweel muddati istemal donon mein muwazna karne wali pehli bari tehqeeq hai.
Dawa badalne ki wajah nahin
Radboud mein mushkil se qaboo aane wale depression ke professor Eric Ruhé ne kaha: “Agar aap antidepressant shuru karen to aisi dawa chunen jo na sirf aap ko theek kare balke theek bhi rakhe.” Unhon ne zor diya ke kisi dawa ke fawaid aur muzir asraat ka tawazun har shakhs ke liye mukhtalif hota hai, is liye dawa ka intikhab mareez ke lihaz se badalta rahega.
Tehqeeq ke pehle musannif Paul van Haaren ne bataya ke agomelatine se jigar fail hone ka khatra hota hai, jabke duloxetine pehle ilaj ke taur par kam tajweez ki jati hai. Escitalopram pehle hi bare paimane par istemal hoti hai.
Azad mahireen ne kaha ke farq mamooli hai. Royal College of Psychiatrists ke Allan Young ne kaha ke yeh farq “muzir asraat, pichhle radd-e-amal aur mareez ki tarjeeh jaise infiradi awamil par bhari parne ka imkan nahin rakhta”. Imperial College London ke Sameer Jauhar ne kaha ke yeh tehqeeq “yeh nahin bata sakti ke kisi khas mareez ke liye kaun si antidepressant behtareen ho gi”, aur jo shakhs apni maujooda dawa se theek hai us ke liye dawa badalne ki koi wajah nahin.
Mareezon ko kya janna chahiye
Tamam dawaon ki tarah escitalopram ke bhi muzir asraat ho sakte hain, jin mein neend ke masail, qabz, aur wazan barhna shamil hain, agarche har kisi ko yeh nahin hote. Doctor umooman mashwara dete hain ke depression khatam hone ke baad kam az kam chhe mah tak antidepressant jari rakhi jaye aur phir tibbi mashware se aahista aahista chhori jaye, kabhi achanak nahin.
Muhaqqiqeen ke mutabiq duniya bhar mein taqriban chhe feesad log depression ka shikar hote hain. Ilaj badalne par ghaur karne wala har shakhs pehle apne doctor se baat kare.
